How the mycotoxin deoxynivalenol exacerbates the genotoxicity of heme iron

Margaux Lalaurie¹, Clemence Rives¹, Marion Garofalo¹, Marie Penary², Sylvie Puel¹, Nathalie Naud¹, Julien Vignard¹, Philippe Pinton¹, Yannick Lippi¹, Gladys Mirey¹, Elodie Rousseau-Bacquie¹, Fabrice Pierre¹, Francoise Gueraud¹, Delphine Payros¹, Isabelle P. Oswald¹

¹Toxalim, Université de Toulouse, INRAE, ENVT, EI-Purpan, Toulouse, France; ²IRSD, Université de Toulouse, INSERM, INRAE, ENVT, UPS, Toulouse, France

Deoxynivalenol disrupts the blood-testis barrier in prepubertal and adult mice: a possible cytokine-mediated effect

Ana Laura Paulino Leite Gomes¹, Juliana Rubira Gerez¹, Marielen de Souza¹, Camila Rodriguez Ferraz², Waldiceu Aparecido Verri Junior², Ana Paula Frederico Rodrigues Loureiro Bracarense¹

¹Laboratory of Animal Pathology, Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil; ²Laboratory of Pain, Inflammation, Neuropathy and Cancer, Department of Immunology, Parasitology and General Pathology, State University of Londrina, Londrina, Brazil

Shaping the immunomodulation in colon: how high glucose conditions modulate the immunomodulatory properties of mycotoxins

Karolina Kowalska¹, Aleksandra Kołacin^1,2, Agnieszka Wanda Piastowska-Ciesielska^1,3

¹Medical University of Lodz, Department of Cell Culture and Genomic Analysis, Lodz, Poland; ²Medical University of Lodz, Division of Biomedical Sciences, Faculty of Medicine, Lodz, Poland; ³Medical University of Lodz, BRaIn Laboratories, Lodz, Poland

Unraveling the toxicokinetics of T-2 and HT-2 toxin in humans and developing a physiologically-based kinetic model

Hannah P. McKeon¹, Marloes A. A. Schepens¹, Joost Westerhout¹, Marta M. Sopel², Ilaria Di Marco Pisciottano², Laura Righetti^2,3, Corinne Sprong¹, Marcel J. B. Mengelers¹, Trine Husøy⁴

¹National Institute for Public Health and the Environment (RIVM), 3720 BA Bilthoven, the Netherlands; ²Wageningen Food Safety Research (WFSR), 6708 WB Wageningen, the Netherlands; ³Laboratory of Organic Chemistry, Wageningen University and Research (WUR), 6708 PB Wageningen, the Netherlands; ⁴Norwegian Institute of Public Health (NIPH), N‐0213 Oslo, Norway

Beyond aflatoxin B1: Mutagenicity assessment and evaluation of topoisomerase-poisoning potential of selected aflatoxin B1 precursors

Noah Ratzer^1,2, Francesco Crudo¹, Laura Soler-Vasco³, Isabelle P. Oswald³, Olivier Puel³, Doris Marko¹

¹Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Vienna, Austria; ²Doctoral School in Chemistry, University of Vienna, Vienna, Austria; ³Toxalim, Research Centre in Food Toxicology, INRAE, Toulouse, France

Acute Toxic Effects of Stachybotrys chartarum Bioaerosols

Stefanie Klar¹, Anja Wolff¹, Jessica Reinert¹, Silke Steinborn¹, Lennart Marske³, Judith Neuhoff³, Marion Berger³, Udo Jäckel², Dierk-Christoph Pöther¹

¹Federal Institute for Occupational Safety and Health, Unit Bioaerosols; ²Federal Institute for Occupational Safety and Health, Section Biological Agents, Biocides; ³Federal Institute for Occupational Safety and Health, Unit Biomonitoring