11:15am - 11:30amThe mycotoxin food contaminant alternariol impedes oxaliplatin-induced immunostimulation
Sonja Hager1, Judith Gufler1, Petra Heffeter2, Doris Marko1
1Department of Food Chemistry and Toxicology, Faculty of Chemistry, University Vienna, Vienna, Austria; 2Center for Cancer Research, Medical University of Vienna, Vienna, Austria
11:30am - 11:45amDigging into the mechanics of alternariol toxicity – spotlighting kinases inhibition at a “kinome” level
Lorenzo Pedroni1, Florinda Perugino1,2, Gianni Galaverna1, Doris Marko3, Chiara Dall'Asta1, Luca Dellafiora1
1Department of Food and Drug, University of Parma, Parma, Italy; 2Department of Biology, University of Naples Federico II, Naples, Italy; 3Department of Food Chemistry and Toxicology, University of Vienna, Vienna, Austria
11:45am - 12:00pmA new level to rise the current understanding of ochratoxin A toxicity from a molecular standpoint: an in silico journey
Lorenzo Pedroni1, Florinda Perugino1,2, Gianni Galaverna1, Chiara Dall'Asta1, Luca Dellafiora1
1Department of Food and Drug, University of Parma, Parma, Italy; 2Department of Biology, University of Naples Federico II, Naples, Italy
12:00pm - 12:15pmDetermination of TK parameters and iTTC of tenuazonic acid through a human toxicokinetic trial and PopTK modelling
Lia Visintin1, En-Hsuan Lu2, Hsing-Chieh Lin2, Truong Nguyen1, Weihsueh Chiu2, Sarah De Saeger1,3, Marthe De Boevre1
1Centre of Excellence in Mycotoxicology and Public Health, Ghent University, Ghent, Belgium; 2Interdisciplinary Faculty of Toxicology, Texas A&M University, College Station, USA.; 3Department of Biotechnology and Food Technology, University of Johannesburg, Gauteng, South Africa
12:15pm - 12:30pmDietary exposure: the mycotoxin deoxynivalenol increases the genotoxicity of haem iron
Delphine Payros1,2, Marion Garofalo1, Margaux Lalaurie1, Marie Penary2, Florence Mompart1, Sylvie Puel1, Nathalie Naud1, Florence Blas-Y-Estrada1, Mikaël Albin1, Aurélia Astruc1, Julien Vignard1, Philippe Pinton1, Gladys Mirey1, Elodie Rousseau-Bacquié1, Fabrice Pierre1, Françoise Guéraud1, Isabelle P. Oswald1
1INRAE, UMR1331, Toxalim, Research Centre in Food Toxicology, Toulouse, France; 2IRSD, Université de Toulouse, INSERM, INRAE, ENVT, UPS, Toulouse, France
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