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Mi-S3.3-SE:Neu2: Sesión Especial: Neurotecnologías II Lugar: Aula 0.02 Presidente de la sesión: Antonio José del Ama Espinosa Presidente de la sesión: Ricardo Ron-Angevin | |
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17:45 - 18:00
Recording elicited and voluntary muscle activity of rodents using high-density electromyography arrays 1: BSICoS Group, Instituto de Investigación en Ingeniería de Aragón (I3A) and Instituto de Investigación Sanitaria (IIS) Aragón, Universidad de Zaragoza, Zaragoza, Spain; 2: Department of Cell Biology, Physiology and Immunology & Institute of Neuroscience, Autonomous University of Barcelona, Barcelona, Spain; 3: Department of Bioengineering, Imperial College London, London, United Kingdom; 4: Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain High-density electromyography (hdEMG) enables the study of motor unit (MU) activity by exploiting the spatial information of multichannel recordings. While myomatrix arrays have recently allowed recordings from awake rodents, thin-film electrodes have so far been restricted to acute or anesthetized preparations. Here we present pilot experiments demonstrating the feasibility of recording MU activity from upper- and lower-limb muscles of rats during natural behaviour using both myomatrix and thin-film arrays. Compound responses were elicited by nerve stimulation to confirm electrode functionality, and individual MU action potentials were observed during both reflexive and voluntary movements. These findings constitute the first demonstration of thin-film arrays in awake rodents and provide valuable insight into surgical protocols, electrode configurations, and acquisition strategies that inform the development of stable hdEMG approaches for future MU decomposition in small-animal models.
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