JavaScript is Disabled
Your browser's JavaScript functionality is disabled. It has to be enabled to use this function of ConfTool.
Here you can find information on how to enable JavaScript
If you have any problems, please contact the organizers at parasitologycommunicator@gmail.com.

Conference Agenda

Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).

Daily Overview

Session

CP8: Drugs & Drug Resistance 1 - 10 min talks
Location: Lecture Theatre 1
Session Chair: Christopher Hart, Griffith University
Session Chair: Hannah Smith, Griffith University

Presentation 5

Defining chemical resistance in the Australian cattle tick (Rhipicephalus australis)

Hannah Siddle¹, Guilherme Klafke², Ala Tabor^1,3

1: The University of Queensland, Queensland Alliance for Agriculture & Food Innovation, Centre for Animal Science, St Lucia 4072, Queensland, Australia; 2: Instituto de Pesquisas Veterinárias Desidério Finamor; Rio Grande do Sul State Government, Eldorado do Sul, Brazil; 3: The University of Queensland, School of Chemistry & Molecular Biosciences, St Lucia 4072, Queensland, Australia

Cattle ticks are a burden on global agriculture, with chemical treatments the primary method of control. However, ticks are being selected for resistance to these chemicals. Current tests for chemical resistance are slow and require laboratory facilities, inhibiting testing. In this project, we aim to undertake deep sequencing to define polymorphisms controlling resistance and build a database for monitoring of resistance changes. In preliminary studies, a survey and sampling system has been established to capture cattle ticks from across the infested range. Based on initial collections, resistance has been assessed across ten properties, defining resistance to synthetic pyrethroids (SP), amitraz, fluazuron and macrocyclic lactones. A newly developed rapid test for chemical resistance (RaTexT^TM) was used to define resistance to a synthetic pyrethroid, deltamethrin. Resistance to deltamethrin has been found at 100% of properties regardless of whether this chemical is currently in use. In contrast, fluazuron resistance was found at 40% of properties and only at properties where it is currently in use. Future work will assess the allele frequencies of the known polymorphism driving SP resistance, kdr, to determine the accuracy of rapid testing methods and deep sequencing will be undertaken on resistant and susceptible ticks for each chemical class.